Scientists at the new LIED Transplant Center at Nebraska Health Systems, University of Nebraska Medical Center, Omaha, Nebraska, conduct advanced biomedical research. One of the main considerations with regard to the Center’s Tri-Stack exhaust systems was proper ventilation of 32 laboratory workstation fume hoods. Since prevention of exhaust re-entrainment was critical, wind tunnel tests were performed using models to determine affects of wind on the facility and surrounding buildings, as well as the surrounding buildings’ affects on the new building. In addition to preventing re-entrainment, architects were concerned with “not having prominent exhaust stacks protruding above the roofline.” These factors—along with odor elimination for neighboring facilities—led to management’s decision to use Tri-Stack systems which exhaust about 70,000 CFM from the 251,000 sq.ft. building.